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Omtrent seven-9 % af den kaukasiske befolkning har variationer i CYP2D6 genet som koder for ingen- eller nedsat aktivitet af CYP2D6 (se personlig medicin ). Tramadol et produg der omdannes til den aktive metabolit by means of CYP2D6. Patienter med nedsat eller manglende aktivitet af CYP2D6, vil have reduceret- eller manglende effekt af tramadol.Mæ
Seychelles has decriminalized the use and possession of little quantities of cannabis for private use. The shift in direction of a far more progressive tactic displays an acknowledgment with the switching global attitudes in the direction of cannabis.Neon weed signals became ubiquitous in Bangkok’s chaotic tourist space, with dispensaries croppin